HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-2,4-dimethoxybenzaldehyde → HCID 67067678, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-2,4-dimethoxybenzaldehyde | HCID 14120946 | — |
| Reactant | 1-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067672 | — |
| Product | HCID 67067678 | HCID 67067678 | 59% |
Reaction Steps
Following the procedure used to prepare 1-(5-fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol, 3-bromo-2,4-dimethoxy-benzaldehyde (0.80 g, 3.26 mmol) [prepared as described in Helv. Chim, Acta, 1990, 73, 48], was reacted to give the title compound (0.67 g, 59%). 1H NMR (400 MHz, DMSO-d6): δ 7.67-7.62 (d, 1H), 7.45-7.35 (m, 5H), 7.01-6.96 (d, 1H), 6.14-6.11 (d, 1H), 5.78-5.74 (d, 1H), 3.88-3.84 (m, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-35a9a7c4c0144e7bb26cc9201db97e58 |
| Source note | uspto-grants-2013_10 |