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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037188Generated: November 1, 2026

3-Iodo-7-methoxy-2-phenyl-4H-1-benzopyran-4-one → {1-[4-(7-Methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1037188

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Iodo-7-methoxy-2-phenyl-4H-1-benzopyran-4-oneHCID 15152170—
Reactant{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl esterHCID 67067635—
Product{1-[4-(7-Methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl esterHCID 67067846100%

Reaction Steps

Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 3-iodo-7-methoxy-2-phenyl-chromen-4-one was reacted to give the title compound (80 mg, 100%) as a colourless oil. LCMS (Method A) RT=4.88 min, [M+H]+=498.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546376B2
Source datasetuspto-grants-2013_10
ORD IDord-de6604ad4295440e9ecaf43d478ae784
Source noteuspto-grants-2013_10