HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-methoxybenzaldehyde → 1-(5-Bromo-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-methoxybenzaldehyde | HCID 90684 | — |
| Reactant | 1-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067672 | — |
| Product | 1-(5-Bromo-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067631 | 69% |
Reaction Steps
Following the procedure used to prepare 1-(5-fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol, 2-methoxy-5-bromobenzaldehyde was reacted to give the title compound as a colourless oil (440 mg, 69%). LCMS (Method B): RT=4.47 min, [M−OH+H]+=299/301.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-e0abc39257074cf0b7f5c0a649308d6c |
| Source note | uspto-grants-2013_10 |