HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,5-dimethoxybenzaldehyde → 1-(4-Bromo-2,5-dimethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,5-dimethoxybenzaldehyde | HCID 777997 | — |
| Reactant | 1-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067672 | — |
| Product | 1-(4-Bromo-2,5-dimethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067731 | 100% |
Reaction Steps
Following the procedure used to prepare 1-(5-fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol, 2,5-dimethoxy-4-bromobenzaldehyde was reacted to give the title compound as a colourless oil (1.45 g, 100%). LCMS (Method B): RT=4.49 min, [M+Na]+=369/371.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-144c927046f1458a87c078b4ffe69f7b |
| Source note | uspto-grants-2013_10 |