(1-{4-[4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → (1-{4-[6-Methoxy-4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester

참여 물질

역할	이름	HCID	투입량
반응물	(1-{4-[4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester	HCID 67067641	—
반응물	{1-[4-(7-Bromo-6-methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester	HCID 67067830	—
생성물	(1-{4-[6-Methoxy-4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester	HCID 68227221	65%

반응 단계

Following the procedure used to prepare (1-{4-[4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester, {1-[4-(7-bromo-6-methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted to give the title compound as a colourless oil (55 mg, 65%). LCMS (Method B): RT=4.90 min, [M+H]+=564.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08546376B2
출처 데이터셋	uspto-grants-2013_10
ORD ID	ord-a2d6ac5c9a83406283b6c0a2706e34be
출처 메모	uspto-grants-2013_10