HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methoxybenzaldehyde → 1-(4-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methoxybenzaldehyde | HCID 2774537 | — |
| Reactant | 1-(2,6-Dimethoxy-pyridin-3-yl)-3-phenyl-prop-2-yn-1-ol | HCID 67067816 | — |
| Product | 1-(4-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067874 | 96% |
Reaction Steps
Following the procedure used to prepare 1-(2,6-dimethoxy-pyridin-3-yl)-3-phenyl-prop-2-yn-1-ol, 4-fluoro-2-methoxy-benzaldehyde was reacted to give the title compound (1.60 g, 96%) as a colourless oil. LCMS (Method A): RT=4.30 min, [M+Na]+=279.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-f5cd59b056d541cfbc9a5a45c126f297 |
| Source note | uspto-grants-2013_10 |