{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → (1-[4-(8-Methoxy-4-oxo-2-phenyl-4H-pyrano[2,3-c]pyridin-3-yl)-phenyl]-cyclobutyl)-carbamic acid tert-butyl ester

Participants

Reaction Steps

Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 3-iodo-8-methoxy-2-phenyl-pyrano[2,3-c]pyridin-4-one was reacted to give the title compound (53.4 mg, 71%) as a white solid. LCMS (Method A): RT=4.91 min, [M+H]+=499.

Provenance & Evidence