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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037314Generated: November 1, 2026

{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → HCID 86671040, compound

https://huagongshe.com/reaction/1037314

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl esterHCID 67067635—
Reactant7-Iodo-8-phenyl-2-(2-trimethylsilanyl-ethoxymethyl)-2H-9-oxa-1,2,3a-triaza-cyclopenta[a]naphthalene-3,6-dioneHCID 86671039—
ProductHCID 86671040HCID 8667104078%

Reaction Steps

Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 7-iodo-8-phenyl-2-(2-trimethylsilanyl-ethoxymethyl)-2H-9-oxa-1,2,3a-triaza-cyclopenta[a]naphthalene-3,6-dione was reacted to give the title compound as a pale yellow gum (24 mg, 78%). LCMS (Method A): RT=5.02 min, [M+H]+=655.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546376B2
Source datasetuspto-grants-2013_10
ORD IDord-cd3c14451da54ff3a046015a5d60e869
Source noteuspto-grants-2013_10