(1-{4-[4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → HCID 178452579, compound

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Following the procedure of (1-{4-[4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester, {1-[4-(8-bromo-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted with 3-(trifluoromethyl)-1H-pyrazole-4-boronic acid pinacol ester to give the title compound as a white solid (35 mg, 64%). LCMS (Method G): RT=4.15 min, [M+H]+=602.

Provenance & Evidence