3-[4-(1-Amino-cyclobutyl)-phenyl]-2-phenyl-7H-pyrano[2,3-e]indazol-4-one → HCID 178507117, compound

Participants

Reaction Steps

Following the procedure used to prepare 3-[4-(1-amino-cyclobutyl)-phenyl]-2-phenyl-7H-pyrano[2,3-e]indazol-4-one, {1-[4-(6-oxo-8-phenyl-1,6-dihydro-9-oxa-1,2,3-triaza-cyclopenta[a]naphthalen-7-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted to give the title compound as a yellow solid (9 mg, 22%). 1H NMR (400 MHz, DMSO-d6): δ 7.75-7.70 (m, 2H), 7.53-7.49 (m, 2H), 7.47-7.37 (m, 5H), 7.34-7.31 (m, 2H), 2.61-2.54 (m, 2H), 2.49-2.39 (m, 2H), 2.19-2.08 (m, 1H), 1.86-1.75 (m, 1H). LCMS (Method E): RT=2.93 min, [M+H]+=409.

Provenance & Evidence