HRID1037368

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67067881

未命名化合物

HCID178432084

未命名化合物

PRODUCTS

产物

HCID67067933

未命名化合物

收率 39%

PROCEDURE

实验过程

Following the procedure used to prepare {1-[4-(2-methyl-6-oxo-8-phenyl-1,6-dihydro-chromeno[7,8-d]imidazol-7-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, {1-[4-(7-amino-8-methylamino-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted to give the title compound as a white solid (40 mg, 39%). LCMS (Method H): RT=3.34 min, [M+H]+=536.

WORKUP

后处理

customwas reacted

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-59a92386eaa84324bb4448a5cd6aadd9
来源数据集: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08546376B2
来源说明: uspto-grants-2013_10

反应SMILES

[C:1]([O:5][C:6](=[O:39])[NH:7][C:8]1([C:12]2[CH:17]=[CH:16][C:15]([C:18]3[C:23](=[O:24])[C:22]4[CH:25]=[CH:26][C:27]5[N:28]=[C:29]([CH3:32])[NH:30][C:31]=5[C:21]=4[O:20][C:19]=3[C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)=[CH:14][CH:13]=2)[CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[C:40](OC(=O)NC1(C2C=CC(C3C(=O)C4C(=C(NC)C(N)=CC=4)OC=3C3C=CC=CC=3)=CC=2)CCC1)(C)(C)C>>[C:1]([O:5][C:6](=[O:39])[NH:7][C:8]1([C:12]2[CH:13]=[CH:14][C:15]([C:18]3[C:23](=[O:24])[C:22]4[CH:25]=[CH:26][C:27]5[N:28]=[C:29]([CH3:32])[N:30]([CH3:40])[C:31]=5[C:21]=4[O:20][C:19]=3[C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)=[CH:16][CH:17]=2)[CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:2])[CH3:3]