反应详情

To a solution of compound (ii) (10 mg, 0.024 mmol) in MeOH (1 mL) was added 10% palladium on carbon (7 mg). The reaction was stirred vigorously under an atmosphere of hydrogen at RT for 2 h. The reaction mixture was filtered to give 5-cyclopropyl-N-methyl-6-[(methylsulfonyl)amino]-2-[4-(propan-2-yl)phenyl]-2H-indazole-3-carboxamide (iii) as a white solid (10 mg, 99%).

1. filtrationThe reaction mixture was filtered