(R)-2-Methyl-CBS-oxazaborolidine → HCID 44553141, compound

Participants

Reaction Steps

The procedure given in Example 1 was followed using tert-butyl(3S)-3-[methoxy(methyl)carbamoyl]piperidine-1-carboxylate was used instead of tert-butyl(3R)-3-[methoxy(methyl)carbamoyl]piperidine-1-carboxylate. As a reducing agent, (R)-2-methyl-CBS-oxazaborolidine was used instead of (S)-2-methyl-CBS-oxazaborolidine. And 1H-[1,2,3]-triazole was used as a reactant, instead of 1H-tetrazole, to give (3S)-3-[(S)-naphthalen-2-yl(2H-1,2,3-triazol-2-yl)methyl]piperidine.

Provenance & Evidence