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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037675Generated: October 31, 2026

Boron tribromide → 5-[4-(3-Hydroxy-pyridin-2-yl)-oxazol-2-yl]-pentanoic acid

https://huagongshe.com/reaction/1037675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoron tribromideHCID 25134—
Reactant5-[4-(3-Methoxy-pyridin-2-yl)-oxazol-2-yl]-pentanoic acid methyl esterHCID 59027828—
Product5-[4-(3-Hydroxy-pyridin-2-yl)-oxazol-2-yl]-pentanoic acidHCID 67169923—

Reaction Steps

Treat 5-[4-(3-methoxy-pyridin-2-yl)-oxazol-2-yl]-pentanoic acid methyl ester with boron tribromide followed by standard hydrolysis to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546581B2
Source datasetuspto-grants-2013_10
ORD IDord-2440bee633e342989be794ff10dfbd62
Source noteuspto-grants-2013_10