Pyridine → HCID 86667142, compound

HRID 1037731Notes

Reaction equation

HRID 1037731 reaction equation
[CH2:1]([S:4]([O:7]C)(=[O:6])=[O:5])[CH:2]=[CH2:3].[N:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:1]([S:4]([O-:7])(=[O:6])=[O:5])[CH:2]=[CH2:3].[CH3:1][N+:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 1049Pyridine2×HCID 21516113HCID 21516113, compound

Product 1

HCID 86667142HCID 86667142, compoundYield 93%

Conditions

Temperature
80 °C

Procedure

Methyl allylsulfonate (21.4 g, 0.157 mol) synthesized by the conventional method and pyridine (13.1 g, 0.166mol, 1.05 eq) were reacted by stirring for 2 hours at 80° C. After completed the reaction, unreacted pyridine was removed under reduced pressure, crude substance was washed with ethyl acetate several times. The desired product of 1-methylpyridinium allylsulfonate (31.4 g, 0.146 mmol, 93% yield) was obtained by drying by heating under reduced pressure. Melting point was 39° C. Measurement result of 1H NMR was shown as follows:

Workup

  1. customwere reacted
  2. customwas removed under reduced pressure
  3. washcrude substance was washed with ethyl acetate several times

Sources & evidence

ORD record
ord-6ab08a99bfd345f7b426d8ee3c6236eb
Source dataset
uspto-grants-2013_10
Patent number
US08546609B2

Reaction notes

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