HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037795Generated: October 29, 2026
Thionyl Chloride → 4-Acetyl-1-naphthalenecarbonyl chloride
https://huagongshe.com/reaction/1037795
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Acetylnaphthalene-1-carboxylic acid | HCID 66866343 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Acetyl-1-naphthalenecarbonyl chloride | HCID 86649801 | 98.7% |
Reaction Steps
Thionyl chloride (35.00 g, 0.29 mol) was added to a solution of 4-acetyl-1-naphthalenecarboxylic acid (51.70 g, 0.24 mol) in toluene (350 mL). The mixture was warmed to 90° C. for 8.5 h. After cooling to 25° C., the solvent was removed under reduced pressure to give the title product as an off-white solid (55.1 g, 98.7% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08546618B2 |
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| Source dataset | uspto-grants-2013_10 |
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| ORD ID | ord-8bec156b00c34eea82723611e18d3ad3 |
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| Source note | uspto-grants-2013_10 |
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