HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037826Generated: November 1, 2026
2-Aminothiazole → 3-(3-methoxypropyl)-1,3-thiazol-2(3H)-imine hydrobromide
https://huagongshe.com/reaction/1037826
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | 1-Bromo-3-methoxypropane | HCID 524551 | — |
| Product | 3-(3-methoxypropyl)-1,3-thiazol-2(3H)-imine hydrobromide | HCID 66859851 | 48% |
Reaction Steps
A mixture of 2-aminothiazole (1.0 g, 10 mmol) and 1-bromo-3-methoxypropane (1.8 g, 12 mmol) were heated at 85° C. for 16 hours. The solid was cooled to ambient temperature, triturated with ethanol, and then collected by filtration to provide 1.2 g (48%) of the title compound. MS (DCI/NH3) m/z 173 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08546583B2 |
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| Source dataset | uspto-grants-2013_10 |
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| ORD ID | ord-f56d0927376c4202a897129aa8f9a1e7 |
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| Source note | uspto-grants-2013_10 |
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