Furan, 2-(bromomethyl)tetrahydro- → 5-ethyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

HRID 1037905Notes

Reaction equation

HRID 1037905 reaction equation
[CH2:1]([C:3]1[S:7][C:6]([NH2:8])=[N:5][CH:4]=1)[CH3:2].Br[CH2:10][CH:11]1[CH2:15][CH2:14][CH2:13][O:12]1>>[CH2:1]([C:3]1[S:7][C:6](=[NH:8])[N:5]([CH2:10][CH:11]2[CH2:15][CH2:14][CH2:13][O:12]2)[CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 14501Furan, 2-(bromomethyl)tetrahydro-HCID 127372575-Ethyl-1,3-thiazol-2-amine

Product 1

HCID 686233365-ethyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

Procedure

A mixture of 5-ethylthiazol-2-amine and 2-(bromomethyl)tetrahydrofuran were processed using the method described in Example 2A to afford the title compound. MS (ESI) m/z 213 (M+H)+.

Sources & evidence

ORD record
ord-f6dd37c484164f98bbb71c2b5bf117e5
Source dataset
uspto-grants-2013_10
Patent number
US08546583B2

Reaction notes

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