HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037933Generated: November 1, 2026
2-Chlorocyclopentanone → 3,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imine
https://huagongshe.com/reaction/1037933
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Chlorocyclopentanone | HCID 12751 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Product | 3,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imine | HCID 332255 | — |
Reaction Steps
A mixture of 2-chlorocyclopentanone (5.0 g, 40 mmol) and thiourea (3.0 g, 40 mmol) was heated at 70° C. for 3 hours. After cooling, the solid was triturated with ethanol and collected by filtration to afford the title compound. MS (ESI) m/z 141 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08546583B2 |
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| Source dataset | uspto-grants-2013_10 |
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| ORD ID | ord-bf1f8d63aae6427da12a69ac79b41b9a |
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| Source note | uspto-grants-2013_10 |
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