HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → HCID 178504261, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 67421026 | HCID 67421026 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178504261 | HCID 178504261 | 71.7% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
To a solution of 29 from Example 62 Step 4 (40 mg, 0.061 mmol) in DMF was added NaN3 (12 mg, 0.18 mmol) and NH4Cl (13 mg, 0.24 mmol). The crude was stirred at 100° C. for 18 hrs. The crude was cool, evaporated, and filtered through a plug of cotton. The crude was evaporated and purified via preparation plate to give 31 mg of a mixture of two isomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546404B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-164968959bdd407c8688f844338b09a7 |
| Source note | uspto-grants-2013_10 |