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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038106Generated: November 2, 2026

Diisopropylethylamine → HCID 86630171, compound

https://huagongshe.com/reaction/1038106

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantHCID 57686143HCID 57686143—
ReactantHCID 86630172HCID 86630172—
SolventDimethylformamideHCID 6228—
ProductHCID 86630171HCID 86630171—

Reaction Steps

3-Methoxy-pyrrolidine-3-carboxylic acid [3-(4-isopropoxy-phenyl)-1H-indazol-5-yl]-amide (8AB) (40 mg, 0.086 mmol, 1 equiv) and 2-Chloro-1-[4-(3-fluoro-4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethanone (7AB) (35 mg, 0.103 mmol, 1.2 equiv) were weighed out in a flask, and to it was added N,N-dimethylformamide (3 mL) and diisopropylethylamine (22 mg, 30 uL, 0.172 mmol, 2 equiv). The reaction content was stirred at room temperature, overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546404B2
Source datasetuspto-grants-2013_10
ORD IDord-12bc4976489c430ca51a43e6f23c1cb5
Source noteuspto-grants-2013_10