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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038107Generated: November 3, 2026

Diisopropylethylamine → HCID 86630173, compound

https://huagongshe.com/reaction/1038107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantHCID 57686143HCID 57686143—
ReactantHCID 76592527HCID 76592527—
SolventDimethylformamideHCID 6228—
ProductHCID 86630173HCID 86630173—

Reaction Steps

3-Methoxy-pyrrolidine-3-carboxylic acid {3-[4-(2-methoxy-ethoxy)-phenyl]-1H-indazol-5-yl}-amide (10AB) (50 mg, 0.103 mmol, 1 equiv) and 2-Chloro-1-[4-(3-fluoro-4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethanone (7AB) (42 mg, 0.124 mmol, 1.2 equiv) were weighed out in a flask and to it was added N,N-dimethylformamide (3 mL) and diisopropylethylamine (26.6 mg, 36 uL, 0.206 mmol, 2 equiv). The reaction content was stirred at room temperature, overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546404B2
Source datasetuspto-grants-2013_10
ORD IDord-4861302744704a93a965adc4f1d1489b
Source noteuspto-grants-2013_10