Methanol → HCID 68527157, compound

Participants

Reaction Steps

Into a Round bottom flask was added tert-butyl 4-(5-nitro-1-trityl-1H-indazol-3-yl)-1H-pyrazole-1-carboxylate (0.440 g, 0.770 mmol) and 10 mL of MeOH and 5 mL of EtOAc followed by Palladium (0.100 g, 0.000470 mmol). The r×n was degassed under Hydrogen (2000 mL, 90 mmol) in balloon, was stirred overnight. TLC (20% EtOAc/Hexane) and MS showed r×n complete. The r×n was filtered through Celite and was rotovaped to dryness to give tert-butyl 4-(5-amino-1-trityl-1H-indazol-3-yl)-1H-pyrazole-1-carboxylate (0.400 g; Yield=95.9%)

Provenance & Evidence