Methanol → HCID 57572471, compound

Participants

Reaction Steps

To a solution of compound 6A in dichloromethane, a mixture of 1 mL methylamine solution (40% wt in water, d=0.902) and isopropanol (10 mL) was added dropwise over 48 h. The reaction mixture was applied directly onto a gradient flash silica column (1-5% methanol in dicholoromethane). The desired product was obtained as a thick, yellow oil. Yield 2.9 g (68% based on methylamine).

Provenance & Evidence