Methanol → HCID 57572474, compound

Participants

Reaction Steps

To a solution of compound 6B (2.3 g, 4.25 mmol) in dichloromethane, a mixture of 0.2 mL methylamine solution (40% wt in water, d=0.902) and 10 mL isopropanol was added dropwise over 24 h, the completeness of reaction was monitored by TLC. The reaction mixture was then directly applied onto a gradient flash silica column (1-5% methanol in dichloromethane). The desired product was obtained as a thick, yellow oil.

Provenance & Evidence