Ethanol → N-(2,3-Dihydro-1H-inden-2-yl)-5-nitro-2-pyridinamine

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-chloro-5-nitropyridine (4 g) and N,N-diisopropylethylamine (3 ml) was heated under reflux in dry ethanol (100 ml) for 2 h. The reaction mixture was cooled to 0° C., the solid which separated was filtered off washed with little cold ethanol, dried to give the product (6.25 g, 88%).

Provenance & Evidence