反应详情

(2S,5R)-tert-butyl 2,5-dimethylpiperazine-1-carboxylate was used in place of (2R,5S)-tert-butyl 2,5-dimethylpiperazine-1-carboxylate for a similar reaction and treatment as the preparation (2R,5S,Z)-3-(2-{4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-(prop-1-en-1-yl)phenyl]-2,5-dimethylpiperazin-1-yl}-2-oxoethyl)-5-[4-(1-methylethoxy)phenyl]-5-methylimidazolidine-2,4-dione of Example 14-1, and the title compound was obtained as a yellow oil.