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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038575Generated: October 31, 2026

5-(2,3-Dihydrobenzofuran-5-yl)-5-methylimidazolidine-2,4-dione → 5-(2,3-Dihydrobenzofuran-5-yl)-3-(2-{4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-propylphenyl]-1,4-diazepan-1-yl}-2-oxoethyl)-5-methylimidazolidine-2,4-dione

https://huagongshe.com/reaction/1038575

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2,3-Dihydrobenzofuran-5-yl)-5-methylimidazolidine-2,4-dioneHCID 66598435—
Reactant2-Bromo-1-(4-{4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl]-2-propylphenyl}-1,4-diazepan-1-yl)ethanoneHCID 86647208—
Product5-(2,3-Dihydrobenzofuran-5-yl)-3-(2-{4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-propylphenyl]-1,4-diazepan-1-yl}-2-oxoethyl)-5-methylimidazolidine-2,4-dioneHCID 59563917—

Reaction Steps

2-Bromo-1-(4-{4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl]-2-propylphenyl}-1,4-diazepan-1-yl)ethanone and 5-(2,3-dihydrobenzofuran-5-yl)-5-methylimidazolidine-2,4-dione were used for a similar reaction and treatment as Examples 14-1 and 15-1, and the title compound was obtained as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08551985B2
Source datasetuspto-grants-2013_10
ORD IDord-2ce930447f164cf295392033d8054a77
Source noteuspto-grants-2013_10