HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloro-2-isocyanatobenzene → 3-(2,6-Dichloro-phenyl)-1-[6-(2,4-difluoro-phenylamino)-pyrimidin-4-yl]-1-methyl-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloro-2-isocyanatobenzene | HCID 604537 | — |
| Reactant | HCID 66669984 | HCID 66669984 | — |
| Product | 3-(2,6-Dichloro-phenyl)-1-[6-(2,4-difluoro-phenylamino)-pyrimidin-4-yl]-1-methyl-urea | HCID 57710226 | — |
Reaction Steps
The title compound is prepared analogously as described in Example 105B from N-(2,4-difluoro-phenyl)-N′-methyl-pyrimidine-4,6-diamine and 2,6-dichlorophenyl isocyanate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552002B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-952c271816984802a11722bf6cea9565 |
| Source note | uspto-grants-2013_10 |