Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038698Generated: October 30, 2026

Benzene, 1-chloro-3-isocyanato- → 3-(3-Chloro-Phenyl)-1-[6-(4-fluoro-phenylamino)-pyrimidin-4-yl]-1-methyl-urea

https://huagongshe.com/reaction/1038698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-chloro-3-isocyanato-HCID 17968—
ReactantN4-(4-fluorophenyl)-N6-methylpyrimidine-4,6-diamineHCID 66669841—
Product3-(3-Chloro-Phenyl)-1-[6-(4-fluoro-phenylamino)-pyrimidin-4-yl]-1-methyl-ureaHCID 57710425—

Reaction Steps

The title compound is prepared analogously as described in Example 121 from N-(4-fluoro-phenyl)-N′-methyl-pyrimidine-4,6-diamine and 3-chlorophenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552002B2
Source datasetuspto-grants-2013_10
ORD IDord-a29a2c15a000433aae1f3edd94090d0a
Source noteuspto-grants-2013_10