3-Chloroaniline → HCID 66669906, compound

HRID 1038700Notes

Reaction equation

HRID 1038700 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][CH3:9])[CH:3]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][CH:17]=1)[NH2:14]>>[Cl:10][C:11]1[CH:12]=[C:13]([NH:14][C:2]2[CH:3]=[C:4]([NH:8][CH3:9])[N:5]=[CH:6][N:7]=2)[CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 79323-ChloroanilineHCID 3094796-chloro-N-methylpyrimidin-4-amine

Product 1

HCID 66669906HCID 66669906, compound

Procedure

The title compound is prepared analogously as described in Example 105A from (6-chloro-pyrimidin-4-yl)-methyl-amine and 3-chloroaniline. The ethyl acetate layer is dried over Na2SO4 and evaporated. The solid residue is suspended in CH2Cl2, filtered off and dried in vacuo to afford the title compound.

Workup

  1. customThe title compound is prepared analogously
  2. dry with materialThe ethyl acetate layer is dried over Na2SO4
  3. customevaporated
  4. filtrationfiltered off
  5. customdried in vacuo

Sources & evidence

ORD record
ord-2d22d33a88b844f594a4b83850478876
Source dataset
uspto-grants-2013_10
Patent number
US08552002B2

Reaction notes

Loading…