3-Chloroaniline → N~4~-(3-chlorophenyl)pyrimidine-4,6-diamine
Reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH2:8])[CH:3]=1.[Cl:9][C:10]1[CH:11]=[C:12]([CH:14]=[CH:15][CH:16]=1)[NH2:13]>>[Cl:9][C:10]1[CH:11]=[C:12]([NH:13][C:2]2[CH:3]=[C:4]([NH2:8])[N:5]=[CH:6][N:7]=2)[CH:14]=[CH:15][CH:16]=1Participants
3
Procedure
The title compound is prepared analogously as described in Example 105A from 6-chloro-pyrimidin-4-ylamine and 3-chloroaniline.
Sources & evidence
- ORD record
- ord-d07e2d6ee66a4f408619e373f7c39e6b
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08552002B2
Reaction notes
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