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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038706Generated: November 1, 2026

2-Isocyanato-1,4-dimethoxybenzene → 1-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,5-dimethoxy-phenyl)-urea

https://huagongshe.com/reaction/1038706

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Isocyanato-1,4-dimethoxybenzeneHCID 4178425—
ReactantN~4~-(3-chlorophenyl)pyrimidine-4,6-diamineHCID 66669982—
Product1-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,5-dimethoxy-phenyl)-ureaHCID 57710333—

Reaction Steps

The title compound is prepared analogously as described in Example 127 from N-(3-chloro-phenyl)-pyrimidine-4,6-diamine and 2,5-dimethoxyphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552002B2
Source datasetuspto-grants-2013_10
ORD IDord-009f666d9cb847e6b1cafefef63c6a21
Source noteuspto-grants-2013_10