1,3-Dichloro-2-isocyanatobenzene → 1-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,6-dichloro-Phenyl)-urea

HRID 1038708Notes

Reaction equation

HRID 1038708 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[CH:14]=[C:13]([NH2:15])[N:12]=[CH:11][N:10]=2)[CH:5]=[CH:6][CH:7]=1.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[C:18]=1[N:24]=[C:25]=[O:26]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:10]=[CH:11][N:12]=[C:13]([NH:15][C:25]([NH:24][C:18]3[C:19]([Cl:23])=[CH:20][CH:21]=[CH:22][C:17]=3[Cl:16])=[O:26])[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6045371,3-Dichloro-2-isocyanatobenzeneHCID 66669982N~4~-(3-chlorophenyl)pyrimidine-4,6-diamine

Product 1

HCID 577102231-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,6-dichloro-Phenyl)-urea

Procedure

The title compound is prepared analogously as described in Example 127 from N-(3-chloro-phenyl)-pyrimidine-4,6-diamine and 2,6-dichlorophenyl isocyanate.

Sources & evidence

ORD record
ord-f8c066d400814211b9abf2786bf6c32f
Source dataset
uspto-grants-2013_10
Patent number
US08552002B2

Reaction notes

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