HCID 68495256, compound → HCID 68493807, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 6-benzyloxy-1-methoxymethyl-1H-indole-2-carboxylic acid ethyl ester (3.45 g, 10 mmol) in EtOH (35 ml) was added 10% Pd/C (0.35 g) and the mixture was stirred under a hydrogen atmosphere (1 atm) for 2 hours at 50° C. The catalyst was filtered off and the filtrate was evaporated. The residue was purified by silica gel column chromatography (n-hexane:AcOEt=4:1) to give 2.0 g of the title compound as colorless crystals.

Provenance & Evidence