HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86646549, compound → HCID 68496504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86646549 | HCID 86646549 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68496504 | HCID 68496504 | 105.6% |
Reaction Steps
[4-(5-Nitropyridin-2-yloxy)indol-1-yl]acetic acid ethyl ester (1.49 g, 4.35 mmol) was dissolved in THF (15 mL). To the solution was added 5% Pd/C (0.15 g) and the resulting solution was subjected to catalytic reduction for 18 hours at room temperature under atmospheric pressure. The catalyst was removed by filtration, and the filtrate was concentrated to yield 1.43 g of the title compound as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08551999B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-6dfeb35643ed4b4e9fa264708dd7591a |
| Source note | uspto-grants-2013_10 |