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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038756Generated: November 1, 2026

HCID 86646549, compound → HCID 68496504, compound

https://huagongshe.com/reaction/1038756

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86646549HCID 86646549—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68496504HCID 68496504105.6%

Reaction Steps

[4-(5-Nitropyridin-2-yloxy)indol-1-yl]acetic acid ethyl ester (1.49 g, 4.35 mmol) was dissolved in THF (15 mL). To the solution was added 5% Pd/C (0.15 g) and the resulting solution was subjected to catalytic reduction for 18 hours at room temperature under atmospheric pressure. The catalyst was removed by filtration, and the filtrate was concentrated to yield 1.43 g of the title compound as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08551999B2
Source datasetuspto-grants-2013_10
ORD IDord-6dfeb35643ed4b4e9fa264708dd7591a
Source noteuspto-grants-2013_10