HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Vanillin → HCID 67229763, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Vanillin | HCID 8991 | — |
| Reactant | 4(3H)-Quinazolinone, 2-methyl-3-phenyl- | HCID 63378 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 67229763 | HCID 67229763 | 75.6% |
Reaction Steps
In a 50 mL round-bottom flask a mixture of compound 27 (0.67 g, 0028 mol), 3-hydroxy-2-methoxy-benzaldehyde (9, 0.003 mol 0.45 g) and NaOAc (0.233 g, 0.002 mol) in AcOH was heated under reflux for 10 hours. After cooling the precipitate formed was filtered off, washed with water, dried and recrystallized from acetic acid to yield 28 (0.56 g, 55%). M. Wt. 370. LCMS [M+H]+=371.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552009B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-f5449b13caf341a48695977174c41599 |
| Source note | uspto-grants-2013_10 |