HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Vanillin → HCID 5111379, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Vanillin | HCID 8991 | — |
| Reactant | 4(3H)-Quinazolinone, 2-methyl-3-(m-tolyl)- | HCID 63135 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 5111379 | HCID 5111379 | 96.4% |
Reaction Steps
In a 50 mL round-bottom flask a mixture of 50 (0.5 g, 002 mol), 2-hydroxy-3 methoxybenzaldehyde (0.4 g, 0.0025 mol) and NaOAc (0.233 g, 0.002 mol) in AcOH was heated under reflux for 10 hours. After cooling the precipitate formed was filtered off, washed with water, dried and recrystallized from acetic acid to yield 51 (0.74 g, 85%). M. Wt. 384. LCMS [M+H]+=385.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552009B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-e37309df76f74f55a94c62272c8bcb5c |
| Source note | uspto-grants-2013_10 |