HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Vanillin → HCID 136400709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Vanillin | HCID 8991 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 3-(3,4-dichlorophenyl)-2-methylquinazolin-4-one | HCID 588867 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 136400709 | HCID 136400709 | 71% |
Reaction Steps
Compound 63 (1 g, 0.028 mol), 2-hydroxy-3 methoxybenzaldehyde (9, 0.4 g, 0.003 mol) and NaOAc (0.233 g, 0.002 mol) in AcOH were heated under reflux for 10 hours. After cooling the precipitate formed was washed with water, filtered off, dried and recrystallized from EtOH to yield 64 (0.55 g, 71%). M. Wt. 439. LCMS [M+H]+=440.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552009B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-a65d247d12a14c8399024d94c6cc28f4 |
| Source note | uspto-grants-2013_10 |