HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid ethyl ester → 6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid ethyl ester | HCID 59167789 | — |
| Reactant | 4-[4-(2-Amino-phenyl)-oxazol-2-yl]-butyric acid | HCID 59799001 | — |
| Product | 6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid | HCID 59167806 | 83.1% |
Reaction Steps
Using a method similar to the procedure described for the preparation of 4-[4-(2-amino-phenyl)-oxazol-2-yl]-butyric acid; hydrolysis of 6-[4-(2-amino-phenyl)-oxazol-2-yl]-hexanoic acid ethyl ester (2.7 g, 8.9 mmol) gives 6-[4-(2-amino-phenyl)-oxazol-2-yl]-hexanoic acid (2.03 g, 83%). MS (ES): (M+1)+ 274.9 m/z.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552039B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-fd348445cb494ef5aa6ee48b6fe9c3f3 |
| Source note | uspto-grants-2013_10 |