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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1039613Generated: October 27, 2026

SS-3227 → (r)-1-[4-(2,3-Epoxypropoxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine

https://huagongshe.com/reaction/1039613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSS-3227HCID 11653258—
Reactant(R)-(-)-Glycidyl-4-nitrobenzenesulfonateHCID 14292098—
Product(r)-1-[4-(2,3-Epoxypropoxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidineHCID 25121192—

Reaction Steps

A target compound was manufactured as in Example 1, using 4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenol and (R)-glycidylnosylate as starting raw materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552188B2
Source datasetuspto-grants-2013_10
ORD IDord-cb6794b165e44fa2bf5a6ab7021b3d30
Source noteuspto-grants-2013_10