Donepezil → HCID 71245930, compound

HRID 1039634Notes

Reaction equation

HRID 1039634 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[CH2:14][CH:13]([CH2:15][CH:16]3[CH2:21][CH2:20][N:19]([CH2:22][C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=4)[CH2:18][CH2:17]3)[C:11](=[O:12])[C:6]2=[CH:7][C:8]=1[O:9][CH3:10]>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[CH2:14][CH:13]([CH2:15][CH:16]3[CH2:17][CH2:18][N:19]([CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)[CH2:20][CH2:21]3)[C:11](=[O:12])[C:6]2=[CH:7][C:8]=1[O:9][CH3:10].[CH3:1][OH:2]

Participants

3

Reactant 1

HCID 3152Donepezil2×

Product 1

HCID 71245930HCID 71245930, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.67 grams or 0.0044 mol of donepezil was added into 1.98 ml of methanol to obtain a mixture and the mixture was heated to 40 degrees Celsius to dissolve the donepezil in order to obtain a donepezil methanol solution.

Workup

  1. customto obtain a mixture
  2. temperaturethe mixture was heated to 40 degrees Celsius

Sources & evidence

ORD record
ord-9042ce6995684336be7f9ff0143433d9
Source dataset
uspto-grants-2013_10
Patent number
US08552195B2

Reaction notes

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