HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-2-(trifluoromethyl)pyridine → (S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-2-(trifluoromethyl)pyridine | HCID 23436940 | — |
| Reactant | (R)-methyl2-(tert-butoxycarbonyl)-3-iodopropanoate | HCID 86614124 | — |
| Product | (S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoate | HCID 67165305 | — |
Reaction Steps
The title compound was prepared according to previously reported procedure (see pending U.S. patent application Ser. No. 11/575,187) from (R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate and 4-iodo-2-(trifluoromethyl)pyridine (this starting material was prepared according to a procedure described in Eur. J. Org. Chem. 2003, 1559-1568).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552181B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-2d8f7d0f182849e1b480ceed4914cfba |
| Source note | uspto-grants-2013_10 |