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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1039796Generated: October 26, 2026

tert-Butanol → Benzenepropanoic acid, 1,1-dimethylethyl ester

https://huagongshe.com/reaction/1039796

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-ButanolHCID 6386—
ReactantMethyl 3-phenylpropionateHCID 7643—
ReactantDiisopropyl EtherHCID 7914—
CatalystZincHCID 23994—
ProductBenzenepropanoic acid, 1,1-dimethylethyl esterHCID 10878309—

Reaction Steps

Under a nitrogen atmosphere, a mixture of methyl 3-phenylpropionate (3.0 mmol), t-butanol (3.6 mmol), the zinc cluster obtained in the above-described Example 5 (0.0375 mmol), and diisopropyl ether (5.0 ml) was refluxed for 18 hours. As a result, t-butyl 3-phenylpropionate was obtained quantitatively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552204B2
Source datasetuspto-grants-2013_10
ORD IDord-92cfc2bc044346c48686b72ca2a7673b
Source noteuspto-grants-2013_10