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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1039800Generated: November 4, 2026

tert-Butanol → HCID 357719, compound

https://huagongshe.com/reaction/1039800

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-ButanolHCID 6386—
ReactantDiisopropyl EtherHCID 7914—
Reactantmethyl N-benzyloxycarbonylglycinateHCID 71033—
CatalystZincHCID 23994—
ProductHCID 357719HCID 35771983.8%

Reaction Steps

Under a nitrogen atmosphere, a mixture of carbobenzyloxyglycine methyl ester (3.0 mmol), t-butanol (3.6 mmol), a zinc cluster Zn4O (OCOCF3)6 (0.0375 mmol), and diisopropyl ether (5.0 ml) was refluxed for 18 hours. As a result, carbobenzyloxyglycine t-butyl ester was obtained in a yield of 83.8%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552204B2
Source datasetuspto-grants-2013_10
ORD IDord-08ff1461eac546688b3c0fa1daccf4c2
Source noteuspto-grants-2013_10