HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → HCID 357719, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | methyl N-benzyloxycarbonylglycinate | HCID 71033 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | HCID 357719 | HCID 357719 | 83.8% |
Reaction Steps
Under a nitrogen atmosphere, a mixture of carbobenzyloxyglycine methyl ester (3.0 mmol), t-butanol (3.6 mmol), a zinc cluster Zn4O (OCOCF3)6 (0.0375 mmol), and diisopropyl ether (5.0 ml) was refluxed for 18 hours. As a result, carbobenzyloxyglycine t-butyl ester was obtained in a yield of 83.8%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552204B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-08ff1461eac546688b3c0fa1daccf4c2 |
| Source note | uspto-grants-2013_10 |