HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4-((tetrahydro-2H-pyran-2-yloxy)methyl)benzyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | (4-{[(Oxan-2-yl)oxy]methyl}phenyl)methanol | HCID 67139706 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | 4-((tetrahydro-2H-pyran-2-yloxy)methyl)benzyl acetate | HCID 68007957 | 84% |
Reaction Steps
Under a nitrogen atmosphere, a mixture of (4-((tetrahydro-2H-pyran-2-yloxy)methyl)phenyl)methanol (6 mmol), a zinc cluster Zn4O (OCOCF3)6 (0.075 mmol), and ethyl acetate (1.7 ml) was refluxed for 18 hours. As a result, 4-((tetrahydro-2H-pyran-2-yloxy)methyl)benzyl acetate was obtained in a yield of 84%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552204B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-c3b04503b5c04b22aada7f04710fab7b |
| Source note | uspto-grants-2013_10 |