ethyl[5,5-dimethyltetrahydro-1'H-spiro[1,3-dioxane-2,2'-pentalen]-5'(3'H)-ylidene]ethanoate → ethyl[5,5-dimethylhexahydro-1'H-spiro[1,3-dioxane-2,2'-pentalen]-5'-yl]acetate

Participants

Reaction Steps

A mixture of the product of Step 2 (400 mg, 1.359 mmol) and 10% Pd—C-50% wet (85 mg, 0.799 mmol) in EtOAc (8.0 mL) was stirred 16 hrs at room temperature under a hydrogen atmosphere. The catalyst was then filtered off and the volatiles were removed under reduced pressure to give ethyl[5,5-dimethylhexahydro-1′H-spiro[1,3-dioxane-2,2′-pentalen]-5′-yl]acetate as a colorless oil. MS ESI: [M+Na]+ m/z 297.7.

Provenance & Evidence