Decanal → HCID 24807838, compound

Participants

Reaction Steps

Synthesized according to the general procedure as described in Example 1a using L-valine methyl ester hydrochloride (1.5 gm, 8.9 mmol), THF (25 mL), MgSO4 (1.81 gm, 15.13 mmol), decanal (3.36 mL, 17.89 mmol), Et3N (1.24 mL, 8.9 mmol), sodium borohydride (677 mg, 17.89 mmol), and methanol (25 mL) to give 11i (1.22 gm, 50%) in FIG. 2. 1H NMR (500 MHz, CDCl3): δ 0.87 (3H, t, J=7.07 Hz), 0.92 (3H, d, J=7.37 Hz), 0.94 (3H, d, J=6.83 Hz), 1.2-1.5 (17H, m), 1.88 (1H, sextet), 2.37-2.44 (1H, m), 2.5-2.8 (1H, m), 2.97 (1H, d, J=6.34 Hz), 3.74 (3H, s). ESI-MS: 294.3 (M+23).

Provenance & Evidence