Decanal → HCID 24808004, compound

Participants

Reaction Steps

Synthesized according to the general procedure as described in Example 1a using D-leucine methyl ester hydrochloride (1.5 gm, 8.25 mmol), THF (20 mL), MgSO4 (1.68 gm, 14.02 mmol), decanal (3.1 mL, 16.5 mmol), Et3N (1.15 mL, 8.25 mmol), sodium borohydride (624 mg, 16.5 mmol), and methanol (30 mL) to give 11o (950 mg, 40%) in FIG. 2. 1H NMR (500 MHz, CDCl3): δ 0.86-0.96 (9H, m), 1.2-1.34 (16H, m), 1.38-1.52 (4H, m), 1.69 (1H, heptet), 2.39-2.48 (1H, m), 2.5-2.58 (1H, m), 3.27 (1H, t, J=7.08 Hz), 3.71 (3H, s). ESI-MS: 308.1 (M+23).

Provenance & Evidence