Oxalic acid dihydrate → HCID 87169893, compound

Participants

Reaction Steps

To a solution of [1R,2R]toluene-4-sulfonic acid 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenyl ester (5 g, 0.01 mol, having purity 96.2% by HPLC) in methanol (10 ml), methanolic solution of oxalic acid dihydrate (1.68 g in 10 ml methanol) was added at ambient temperature and stirred for 15 minutes. Solvents were distilled off from the reaction mixture. To the residue ethyl acetate was added and resulting solid was filtered to give 3.93 g of title compound having purity 98.3% by HPLC.

Provenance & Evidence